Fusogenic Liposome-Coated Nanoparticles  

Breakthrough – Silicon nanoparticles can load and protect high quantities of nucleic acids (siRNA, mRNA, DNA) without the use of cytotoxic polymer stabilizers. When formulated as fusogenic liposome-coated nanoparticles, the nucleic acid is delivered to the cytosol bypassing endosomal uptake and degradation.  Furthermore, these particles may be coated with targeting peptides for delivery to specific cell populations.

Safe Efficient RNA/Gene Delivery using Nanoporous Silicon Particles